ABSTRACT
Cutaneous involvement associated to multiple myeloma varies from 5 to 10% of cases and is infrequently recognized. Cutaneous metastatic plasmacitomas are rare. We present the case of a 72-year-old man with multiple myeloma in complete remission since 2 years ago with cutaneous tumors on the trunk and face. A cutaneous biopsy was consistent with plasmacytoma. The patient was treated with melphalan, prednisolone and radiotherapy. Despite optimal therapeutic response of the lesions, the disease progressed, with the appearance of new extra-cutaneous plasmocytomas. The cutaneous metastatic plasmocytomas were the first sign of progression of the disease.
Subject(s)
Humans , Male , Aged , Plasmacytoma/secondary , Skin Neoplasms/secondary , Multiple Myeloma/pathology , Skin/pathology , Biopsy , Bone Marrow/pathology , Immunohistochemistry , Disease ProgressionABSTRACT
Foram entrevistadas 500 mulheres com vida sexual ativa para saber se usavam algum método anticoncepcional. Das 350 que usavam a anticoncepçäo, avaliou-se o nível de instruçäo, o estado civil, a média de gestaçöes e de abortamentos praticados. Investigou-se o método anticoncepcional preferido de acordo com as diversas faixas etárias do grupo entrevistado. Considerando que a "pílula" é o método de escolha da maioria, investigou-se particularidades de seu emprego